🩸 Blood Work Requirements

Bloodwork is one of the most important steps before starting any peptide protocol. It establishes your baseline health, identifies contraindications, and gives you data to track your progress and safety.

Why Bloodwork Matters

Establishes your baseline before any changes

Identifies contraindications that could make a peptide dangerous

Allows you to objectively track progress and side effects

Required by most clinics before prescribing peptides

Required — Clinics Won't Prescribe Without It

These peptides have strong medical reasons for mandatory bloodwork. Most clinics and telehealth providers require labs before prescribing.

SemaglutideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+3 more

Every 3-6 months while on therapy

HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+2 more

Every 3-6 months while on therapy

TirzepatideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+3 more

Every 3-6 months while on therapy

LiraglutideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+2 more

Every 3-6 months while on therapy

DulaglutideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+1 more

Every 3-6 months while on therapy

ExenatideRequired
HbA1cFasting Blood GlucoseKidney Function (BMP/CMP)Lipid Panel+1 more

Every 3-6 months while on therapy

RetatrutideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+2 more

Every 2-3 months during use (investigational)

SurvodutideRequired
HbA1cFasting Blood GlucoseLipid PanelLiver Function Panel (AST/ALT)+1 more

Every 2-3 months during use (investigational)

CagrilintideRequired
HbA1cFasting Blood GlucoseLipid PanelKidney Function (BMP/CMP)+1 more

Every 3-6 months while on therapy

IGF-1Fasting Blood GlucoseFasting InsulinHbA1c+3 more

Fasting glucose at 2 weeks, full panel at 4-6 weeks, then every 2-3 months

TesamorelinRequired
IGF-1Fasting Blood GlucoseHbA1cLiver Function Panel (AST/ALT)+1 more

IGF-1 at 4-6 weeks, then every 3 months. Discontinue if IGF-1 >3x ULN

IGF-1Fasting Blood GlucoseFasting InsulinHbA1c+1 more

IGF-1 and fasting glucose at 4 weeks, then every 3 months

Total TestosteroneFree TestosteroneLH (Luteinizing Hormone)FSH (Follicle-Stimulating Hormone)+3 more

Hormone panel at 4 weeks, then every 2-3 months

GonadorelinRequired
Total TestosteroneFree TestosteroneLH (Luteinizing Hormone)FSH (Follicle-Stimulating Hormone)+2 more

Hormone panel at 4-6 weeks, then every 3 months

TriptorelinRequired
Total TestosteroneFree TestosteroneLH (Luteinizing Hormone)FSH (Follicle-Stimulating Hormone)+2 more

Hormone panel 2-4 weeks after dose, then monthly until recovery confirmed

IGF-1 LR3Required
IGF-1Fasting Blood GlucoseFasting InsulinHbA1c+2 more

IGF-1 and fasting glucose at 2-4 weeks, then every 2-3 months

IGF-1 DESRequired
IGF-1Fasting Blood GlucoseFasting InsulinLiver Function Panel (AST/ALT)

IGF-1 and fasting glucose at 2 weeks, then every 2-3 months

InsulinRequired
Fasting Blood GlucoseHbA1cFasting InsulinC-Peptide+3 more

Blood glucose before EVERY use. Full panel every 1-2 months

Recommended — Strongly Advised

Bloodwork is strongly recommended to monitor safety and effectiveness. Some clinics may require it; responsible use demands it.

IGF-1Fasting Blood GlucoseFasting InsulinHbA1c+2 more

IGF-1 and fasting glucose at 4-6 weeks, then every 3 months

IGF-1Fasting Blood GlucoseFasting InsulinThyroid Panel (TSH, T3, T4)

IGF-1 at 6 weeks, then every 3 months

IGF-1Fasting Blood GlucoseFasting InsulinThyroid Panel (TSH, T3, T4)+1 more

IGF-1 and fasting glucose at 4-6 weeks, then every 3 months

IpamorelinRecommended
IGF-1Fasting Blood GlucoseFasting InsulinCortisol

IGF-1 at 6 weeks, then every 3 months

SermorelinRecommended
IGF-1Fasting Blood GlucoseThyroid Panel (TSH, T3, T4)Fasting Insulin

IGF-1 at 6 weeks, then every 3-6 months

IGF-1Fasting Blood GlucoseFasting InsulinThyroid Panel (TSH, T3, T4)

IGF-1 and fasting glucose at 4-6 weeks, then every 3 months

GHRP-2Recommended
IGF-1Fasting Blood GlucoseFasting InsulinProlactin+1 more

IGF-1 and prolactin at 6 weeks, then every 3 months

GHRP-6Recommended
IGF-1Fasting Blood GlucoseFasting InsulinProlactin+1 more

IGF-1 and prolactin at 6 weeks, then every 3 months

HexarelinRecommended
IGF-1Fasting Blood GlucoseProlactinCortisol+1 more

IGF-1 and prolactin at 4 weeks, then every 2-3 months

Blood Pressure (baseline reading)Liver Function Panel (AST/ALT)Kidney Function (BMP/CMP)Hormone Panel (Testosterone, Estradiol)

As needed — typically used on-demand, not continuously

Melanotan IIRecommended
Blood Pressure (baseline reading)Liver Function Panel (AST/ALT)Kidney Function (BMP/CMP)Skin Cancer Screening+1 more

Dermatological check before and during use; blood panel every 3-6 months

Optional — Nice to Have

General baseline panels are helpful but not strictly required for these peptides.

Melanotan IOptional
Liver Function Panel (AST/ALT)Skin Cancer ScreeningBlood Pressure (baseline reading)

Dermatological check before and after tanning cycle

📋 General Baseline Panel for Any Peptide

Even if your peptide doesn't have specific requirements, these tests provide a useful health baseline:

CBC (Complete Blood Count)

General health, immune function, blood cell counts

CMP (Comprehensive Metabolic Panel)

Kidney, liver, electrolytes, glucose

Lipid Panel

Cholesterol, triglycerides, cardiovascular risk

Thyroid Panel (TSH)

Thyroid function baseline

Hormone Panel (if applicable)

Testosterone, estradiol, IGF-1 depending on goals

HbA1c

3-month blood sugar average

🏥 How to Get Bloodwork

Your Doctor / Primary Care

Ask your doctor to order labs. Most insurance covers routine bloodwork. Simply tell them you'd like a comprehensive metabolic and hormone panel.

Direct-to-Consumer Labs

Services like Quest Diagnostics, LabCorp, and Ulta Lab Tests allow you to order your own bloodwork without a doctor's order in most US states. Results typically in 1-3 business days.

Telehealth / Peptide Clinics

Many telehealth peptide clinics include bloodwork as part of their onboarding. They'll send you a lab order and review results before prescribing.

At-Home Testing

Companies like Marek Health, InsideTracker, and Everlywell offer at-home blood testing kits. Convenient but may have limited panel options.

⚠️ This information is for educational purposes only and does not constitute medical advice. Always consult a qualified healthcare professional before starting any peptide protocol. Bloodwork requirements may vary by provider and jurisdiction.